● TIER 1 — FDA-approved / recognizedGRADE BSkin / collagen
Collagen peptides
Food/dietary supplement. Research verification: Yes (TGA pending). Origin: Japan. Citations verified: yes. 4 human study record(s) in the FitClinicMD studies database.
GOALS · Skin · Recovery / injury
FDA status
Dietary supplement / food; not a drug.
Compounding (503A/503B)
N/A.
DEA
Not controlled.
WADA (sport)
Not listed on 2026 Prohibited List (no matching section found)
Mechanism
Hydrolysate di/tripeptides.
Human evidence · 4
Meta-analysis knee OA pain. Analgesic efficacy of collagen peptide in knee osteoarthritis: a meta-analysis of randomized controlled trials.
Meta-analysis, 19 RCTs, n=1,125: skin hydration/elasticity. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
Inoue N et al. J Sci Food Agric 2016.
Cicero AFG et al. Am J Hypertens 2013 (Europeans).
Reference only. This page summarizes publicly available regulatory and research information about Collagen peptides. It is not a prescription, an endorsement, or an offer to dispense, and regulatory status can change. Clinicians should verify current status before prescribing or compounding.